PsychENCODE Consortium

Description

The PsychENCODE Consortium has a collective goal of accelerating discovery of non-coding functional genomic elements in human brain, and elucidating their role in the molecular pathophysiology of psychiatric disorders. Research from the PsychENCODE Consortium can be divided into two phases, each with an associated collection of papers. Phase I of the project was published on Dec 14, 2018 in a collection of 11 papers in Science, Science Translational Medicine, and Science Advances. Phase II of the project focused on single-cell and spatial data, culminating in a collection of 14 papers published on May 24, 2024 (9 in Science, 3 in Science Advances, 1 in Scientific Reports, and 1 in Molecular Psychiatry).

Access to Data

Phase I data are not currently available as they are being migrated to the NIMH Data Archive (NDA). Access to Phase II data is managed by the NRGR Access Request system, but the data are distributed through the Synapse system. To access the PsychENCODE Phase II data, applicants must first register for a Synapse account and obtain a Synapse data access token on the PsychENCODE Consortium Knowledge Portal. Applicants must then complete NRGR access request. The applicant's Synapse token must be included in the cover letter within the NRGR submission package along with the other required documents. Investigators using PsychENCODE data in publications should include this acknowledgement.

Please note that the NRGR does not have any biomaterials associated with the PsychENCODE Consortium data.

Funding and Leadership

Data were generated as part of the PsychENCODE Consortium. Visit 10.7303/syn26365932 for a complete list of grants and PIs.

Additional information about the PsychENCODE Consortium can be found at the PsychENCODE website.