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Induced Pluripotent Stem Cells

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Induced Pluripotent Stem Cells 11.6

The Induced Pluripotent Stem Cell (IPSC) Distribution v11.6 was published on 2025-02-12. IPSC distribution v11.6 includes 1546 subjects, 1512 of whom have at least one biosample on record at the repository. There are 830 IPSCs, 627 FCLs, and 8 OEs as of the release. In addition to case/control studies, the IPSC collection includes 11 family studies.

Standard Data & Documentation

  • Distribution Bundle [ or ]: Standard files across disorders, containing demographic, diagnostic, and pedigree information. Sampled (formerly IBX) sample IDs (nrgr_bio_id) and consent level are also provided. Bundle includes data dictionaries.
  • Study Descriptions.
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Additional Data Files

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

Clinical Instruments

iPSC Submitter Form

  • Study 101 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Clinical Instruments

iPSC Submitter Form

  • Study 115 Singec iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Other

  • Phenotypic Data [ or ] Includes demographics, diagnoses, body measurements, brain scan data, and summary data from ADI-R, ADOS, Mullen, SRS instruments. Additional subjects for study 115 can be found in the Phelan-McDermid Syndrome (PMS) collection.

Clinical Instruments

iPSC Submitter Form

  • Study 116 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Other

  • Phenotypic Data [ or ] Includes item-level data for ADI, ADOS, DAS, Mullen, Vineland, and WISC instruments, along with NDA linking IDs.

Clinical Instruments

Other

  • Phenotypic Data [ or ] Includes demographics, diagnosis, and summary data from ADI, ADOS, and Stanford-Binet

Clinical Instruments

iPSC Submitter Form

  • Study 125 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Other

  • Study 125 Cdf Phen [ or ] Data from IBX Cell Deposit Form

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

Clinical Instruments

iPSC Submitter Form

  • Study 130 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Other

  • Study 130 Cdf Phen [ or ] Data from IBX Cell Deposit Form

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

Clinical Instruments

iPSC Submitter Form

  • Study 136 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

Clinical Instruments

iPSC Submitter Form

  • Study 146 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Other

  • Study 146 Cdf Phen [ or ] Data from IBX Cell Deposit Form

Clinical Instruments

Other

  • Phenotypic Data [ or ] Includes summary data for family history and diagnoses.

Clinical Instruments

iPSC Submitter Form

  • Study 159 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Other

  • Study 159 Cdf Phen [ or ] Data from IBX Cell Deposit Form

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

Clinical Instruments

iPSC Submitter Form

  • Study 161 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

This study does not have any additional genetic or clinical data. All study data is included in the standard distribution files above.

Clinical Instruments

iPSC Submitter Form

  • Study 166 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Other

  • Study 166 Phenotypic Data [ or ] s166-misc-phen (n=8) includes medications at time of biopsy and Children’s Global Assessment Score.
  • Study 166 Cdf Phen [ or ] Data from IBX Cell Deposit Form

Clinical Instruments

iPSC Submitter Form

  • Study 175 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Clinical Instruments

iPSC Submitter Form

  • Study 182 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Clinical Instruments

iPSC Submitter Form

  • Study 184 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Clinical Instruments

iPSC Submitter Form

  • Study 192 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Clinical Instruments

iPSC Submitter Form

  • Study 195 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Clinical Instruments

Other

  • Study 200 Phenotypic Data [ or ] (n=17) includes autism and developmental assessment summary score data.

Clinical Instruments

iPSC Submitter Form

  • Study 201 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 101 — Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder

  • Study 101 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 115 — Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using iPSCs

  • Study 115 Singec iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 116 — Cellular and Genetic Correlates of Increased Head Size in Autism Spectrum Disorder Autism Spectrum Disorder

  • Study 116 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 125 — Analysis of Glutamatergic Neurons Derived from Patient Specific iPS Cells

  • Study 125 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 130 — Genomics-Guided Characterization of iPS Cells from Common Mental Illnesses

  • Study 130 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 136 — Integrative Molecular and Phenotype Analysis of 22q11.2 Deletion Syndrome

  • Study 136 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 146 — Induced Neuronal Cells: A Novel Approach to Study Neuropsychiatric Diseases

  • Study 146 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 159 — A chimeric brain model to study human neurological diseases

  • Study 159 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 161 — iPSC-derived human cortical interneurons as developmental model of Schizophrenia neuropsychiatric disease

  • Study 161 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 166 — Juvenile Onset Schizophrenia iPSCs

  • Study 166 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 175 — Neurobiology of Autism With Macrocephaly

  • Study 175 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 182 — Systematic Functional Interpretation of Regulatory Variants in Schizophrenia

  • Study 182 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 184 — iPSC-based platform development for major psychiatric disorder modeling and discovery

  • Study 184 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 192 — Modeling the Human Neuronal Phenotype of the Schizophrenia-Associated 3q29 Deletion

  • Study 192 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 195 — Large-scale reprogramming and expression analysis of patient-derived neural cells in schizophrenia

  • Study 195 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 201 — Cellular, molecular, and functional imaging approaches to understanding early neurodevelopment in autism. Project 3: Biological substrates of risk and resilience using patient-derived stem cells

  • Study 201 iPSC Submitter Form [ or ] The iPSC Submitter Form contains one row per iPSC line received, and records the provenance of the cell line (source/parental cell line IDs), genetic diagnosis and/or modifications, passage number, cell growth conditions and reprogramming conditions at the time of cell line submission. For final conditions after successful regrowth and banking at IBX, see the Certificate of Analysis.

Study 115 — Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using iPSCs

  • Phenotypic Data [ or ] Includes demographics, diagnoses, body measurements, brain scan data, and summary data from ADI-R, ADOS, Mullen, SRS instruments. Additional subjects for study 115 can be found in the Phelan-McDermid Syndrome (PMS) collection.

Study 116 — Cellular and Genetic Correlates of Increased Head Size in Autism Spectrum Disorder Autism Spectrum Disorder

  • Phenotypic Data [ or ] Includes item-level data for ADI, ADOS, DAS, Mullen, Vineland, and WISC instruments, along with NDA linking IDs.

Study 117 — Autism iPSCs for Studying Function and Dysfunction in Human Neural Development

  • Phenotypic Data [ or ] Includes demographics, diagnosis, and summary data from ADI, ADOS, and Stanford-Binet

Study 125 — Analysis of Glutamatergic Neurons Derived from Patient Specific iPS Cells

  • Study 125 Cdf Phen [ or ] Data from IBX Cell Deposit Form

Study 130 — Genomics-Guided Characterization of iPS Cells from Common Mental Illnesses

  • Study 130 Cdf Phen [ or ] Data from IBX Cell Deposit Form

Study 146 — Induced Neuronal Cells: A Novel Approach to Study Neuropsychiatric Diseases

  • Study 146 Cdf Phen [ or ] Data from IBX Cell Deposit Form

Study 158 — Modeling schizophrenia using iPSC neurons

  • Phenotypic Data [ or ] Includes summary data for family history and diagnoses.

Study 159 — A chimeric brain model to study human neurological diseases

  • Study 159 Cdf Phen [ or ] Data from IBX Cell Deposit Form

Study 166 — Juvenile Onset Schizophrenia iPSCs

  • Study 166 Phenotypic Data [ or ] s166-misc-phen (n=8) includes medications at time of biopsy and Children’s Global Assessment Score.
  • Study 166 Cdf Phen [ or ] Data from IBX Cell Deposit Form

Study 200 — Mechanisms of Circuit Failure and Treatments in Patient-derived Neurons in Autism

  • Study 200 Phenotypic Data [ or ] (n=17) includes autism and developmental assessment summary score data.